15,002 research outputs found

    In-medium formation of quarkonium

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    We confront preliminary RHIC data on J/Psi production in nuclear interactions with expectations which follow in scenarios involving charm quark recombination in a region of color deconfinement. The focus is on transverse momentum and rapidity spectra of the J/Psi, which carry a memory of the spectra of the charm quarks. In such a scenario, one predicts that both spectra will be narrower than those expected without recombination. Preliminary results for the transverse momentum spectra point toward a preference for the recombination picture, while the rapidity spectra do not exhibit any narrowing within present large uncertainties. We present new calculations in the recombination model for the centrality behavior of these signals, which map out the necessary experimental precision required for a definitive test.Comment: Based on invited talk at Strangeness in Quark Matter 2006, UCLA, March 26-31, 2006. Clarifying remarks added in published journal versio

    Does Cell Lineage in the Developing Cerebral Cortex Contribute to its Columnar Organization?

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    Since the pioneer work of Lorente de Nó, Ramón y Cajal, Brodmann, Mountcastle, Hubel and Wiesel and others, the cerebral cortex has been seen as a jigsaw of anatomic and functional modules involved in the processing of different sets of information. In fact, a columnar distribution of neurons displaying similar functional properties throughout the cerebral cortex has been observed by many researchers. Although it has been suggested that much of the anatomical substrate for such organization would be already specified at early developmental stages, before activity-dependent mechanisms could take place, it is still unclear whether gene expression in the ventricular zone (VZ) could play a role in the development of discrete functional units, such as minicolumns or columns. Cell lineage experiments using replication-incompetent retroviral vectors have shown that the progeny of a single neuroepithelial/radial glial cell in the dorsal telencephalon is organized into discrete radial clusters of sibling excitatory neurons, which have a higher propensity for developing chemical synapses with each other rather than with neighboring non-siblings. Here, we will discuss the possibility that the cell lineage of single neuroepithelial/radial glia cells could contribute for the columnar organization of the neocortex by generating radial columns of sibling, interconnected neurons. Borrowing some concepts from the studies on cell–cell recognition and transcription factor networks, we will also touch upon the potential molecular mechanisms involved in the establishment of sibling-neuron circuits

    ITSM automation - Using machine learning to predict incident resolution category

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    Problem resolution is a key issue in the IT service industry, and it is still difficult for large enterprises to guarantee the service quality of the Incident Management (IM) process because of the difficulty in handling frequent incidents timely, even though IT Service Management (ITSM) standard process have already been established (Zhao & Yang, 2013). In this work, we propose an approach to predict the incident solution category, by exploring and combining the application of natural language processing techniques and machine learning algorithms on a real dataset from a large organization. The tickets contain information across a vast range of subjects from inside the organization with a vocabulary specific to these subjects. By exploring the text-based attributes, our findings show that the full description of an incident is better than the short description and after stop words removal, the use of additional preprocessing techniques and the addition of tickets nominal attributes such as have no impact to the classification performance.info:eu-repo/semantics/acceptedVersio

    Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology.

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    BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.info:eu-repo/semantics/publishedVersio

    Magnetic monopole and string excitations in a two-dimensional spin ice

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    We study the magnetic excitations of a square lattice spin-ice recently produced in an artificial form, as an array of nanoscale magnets. Our analysis, based upon the dipolar interaction between the nanomagnetic islands, correctly reproduces the ground-state observed experimentally. In addition, we find magnetic monopole-like excitations effectively interacting by means of the usual Coulombic plus a linear confining potential, the latter being related to a string-like excitation binding the monopoles pairs, what indicates that the fractionalization of magnetic dipoles may not be so easy in two dimensions. These findings contrast this material with the three-dimensional analogue, where such monopoles experience only the Coulombic interaction. We discuss, however, two entropic effects that affect the monopole interactions: firstly, the string configurational entropy may loose the string tension and then, free magnetic monopoles should also be found in lower dimensional spin ices; secondly, in contrast to the string configurational entropy, an entropically driven Coulomb force, which increases with temperature, has the opposite effect of confining the magnetic defects.Comment: 8 pages. Accepted by Journal of Applied Physics (2009

    Population expansion in the North African Late Pleistocene signalled by mitochondrial DNA haplogroup U6

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    Background <br/> The archaeology of North Africa remains enigmatic, with questions of population continuity versus discontinuity taking centre-stage. Debates have focused on population transitions between the bearers of the Middle Palaeolithic Aterian industry and the later Upper Palaeolithic populations of the Maghreb, as well as between the late Pleistocene and Holocene. <br/> Results Improved resolution of the mitochondrial DNA (mtDNA) haplogroup U6 phylogeny, by the screening of 39 new complete sequences, has enabled us to infer a signal of moderate population expansion using Bayesian coalescent methods. To ascertain the time for this expansion, we applied both a mutation rate accounting for purifying selection and one with an internal calibration based on four approximate archaeological dates: the settlement of the Canary Islands, the settlement of Sardinia and its internal population re-expansion, and the split between haplogroups U5 and U6 around the time of the first modern human settlement of the Near East. <br/> Conclusions <br/> A Bayesian skyline plot placed the main expansion in the time frame of the Late Pleistocene, around 20 ka, and spatial smoothing techniques suggested that the most probable geographic region for this demographic event was to the west of North Africa. A comparison with U6's European sister clade, U5, revealed a stronger population expansion at around this time in Europe. Also in contrast with U5, a weak signal of a recent population expansion in the last 5,000 years was observed in North Africa, pointing to a moderate impact of the late Neolithic on the local population size of the southern Mediterranean coast

    Monte Carlo study of the critical temperature for the planar rotator model with nonmagnetic impurities

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    We performed Monte Carlo simulations to calculate the Berezinskii-Kosterlitz-Thouless (BKT) temperature TBKTT_{BKT} for the two-dimensional planar rotator model in the presence of nonmagnetic impurity concentration (ρ)(\rho). As expected, our calculation shows that the BKT temperature decreases as the spin vacancies increase. There is a critical dilution ρc0.3\rho_c \approx 0.3 at which TBKT=0T_{BKT} =0. The effective interaction between a vortex-antivortex pair and a static nonmagnetic impurity is studied analytically. A simple phenomenological argument based on the pair-impurity interaction is proposed to justify the simulations.Comment: 5 pages, 5 figures, Revetex fil

    Innovativeness, innovation behavior and performance in the Portuguese hotel industry

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    This work investigates hotel innovation activity based on 11 hotel-specific innovation dimensions and antecedents. Results from a sample of 326 Portuguese hotels showed a high level of Innovativeness in the Portuguese hospitality industry. Information and Communication Technology, and Marketing were the leading innovation areas. The moderate level of Innovation Behavior demonstrates the dominance of incremental innovations. Hotel Size, Hotel Stars, Hotel Chain, and Personnel Training are significantly related to Innovation Behavior. Hotel Innovativeness positively impacted hotel Innovation Behavior, and hotel Innovation Behavior positively impacted hotel Performance. These findings provide both scholars and practitioners with relevant insights into hotel innovation in Portugal.info:eu-repo/semantics/publishedVersio
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